“He [Samuel Guthrie] - for reasons best known to himself - mixed together two gallons of whiskey with a couple of pounds of chlorinated lime. He put them together and then fed this substance to his daughter. She took a sip, declared it quite delicious then passed out. He decided to market it as a stimulant; he never realized that, in fact, it was an anesthetic.”
Samuel Guthrie, discovered chloroform independently in 1831 (Blood and Guts: A History of Surgery - Bloody Beginnings)
Totally legit ways to develop drugs.